cees dekker - An Overview
cees dekker - An Overview
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‘Certainly, that's about suitable. I look for a Bodily idea of biological programs inside of a bottom-up way. I believe you could possibly distinguish three lines of investigation in my team in the meanwhile. The main issues chromosome framework: How does one obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic mobile? We have created visualisation tactics that make it possible for us to check how, for instance, SMC proteins loop DNA (video clip on Youtube) so as to build up chromosomes.
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Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on single molecules and steel clusters
We acquire position-of-care diagnostics exam of neglected tropical disorders in resource-limited configurations, determined by Crspr/Cas9 detecting of pathogen’s DNA in entire body fluids.
From the several years adhering to these discoveries, my analysis passions shifted to biophysics and nanobiology, and I turned fewer involved with the development of nanotube electronics. The focus of numerous researchers in the field also shifted to graphene (where by, funnily plenty of, the primary graphene ribbons have been described as ‘nanotubes that are Slice open along their duration’) soon after the discovery of The 2-dimensional materials in 2004.
We shape bacteria into sorts that deviate from their purely natural phenotype. Specially, I'll present our capability to shape Are living E. coli micro organism into novel designs like rectangles, squares, triangles and circles.
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Right now, we also recognized that it should be achievable to utilize one semiconducting carbon nanotube to generate a transistor — and we set out to make it. We stretched person semiconducting nanotubes across metallic electrodes and used the fundamental silicon substrate for a gate electrode, developing The fundamental three-terminal structure of the discipline-result transistor (Fig.
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Cees Dekker is Distinguished University Professor at TU Delft. Educated like a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes inside the nineties. Given that 2000, he moved to single-molecule biophysics and nanobiology. His present study focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, especially SMC motor protein; and (iii) creating a residing synthetic cell from lifeless molecules. Dekker is an elected member of the KNAW and fellow to the APS and the IOP.
Developments in nanotechnology inside the nineties created constructing electronic units from solitary molecules a likelihood. Cees Dekker recounts how his crew developed a area-temperature transistor determined by one carbon nanotube.
2013, managed shaping of Reside bacterial cells into arbitrary shapes; and discovery of spontaneous fluctuations from the handedness of histone tetrasomes